Pharmacy Resident Publications

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    Exploring the Impact of a Vicarious Learning Approach on Student Pharmacists' Professional Identity Formation Using a Simulated Pharmacist-Patient Encounter.
    (Pharmacy : a journal of pharmacy education and practice, 11/16/2023) Briceland, Laurie L; Dudla, Courtney ++; Watson, Alexandra; Denvir, Paul
    Purposefully developed professional identity formation (PIF) learning activities within the didactic curriculum provide crucial groundwork to complement PIF within authentic settings. The aim of this didactic exercise was to explore the impact upon student pharmacists' PIF after viewing, analyzing, and reflecting upon a simulated pharmacist-patient encounter (PPE). A 12 min role-play video was created, featuring a pharmacist counseling a standardized patient on a new medication regimen; foundational principles of medication safety, health literacy, social determinants of health, empathic communication, and motivational interviewing were included in the counseling, with some aspects intentionally performed well, others in need of improvement. Also included were the patient's varied reactions to the counseling. Students assumed the observer role and learned vicariously through viewing the PPE. Postactivity debriefs included justifying a foundational principle performed well by the pharmacist, and another in need of improvement, and a self-reflection essay expressing the impact of viewing the PPE on their PIF, from which extracts were thematically analyzed for impact. The main themes of the impact included increased awareness of counseling techniques, patient-friendly medical jargon, patient perspectives/empathy, positive and negative pharmacist role-modeling, and the value of the observer role. This PPE exercise enhanced PIF in terms of students thinking, acting, and feeling like a pharmacist, based on students' self-reflections, which most often referenced effective pharmacist-patient communication and enacting optimal patient care.
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    Thyroid Disorders
    (Pharmacotherapy Principles and Practice Study Guide: A Case Based Care Plan Approach, 6e, 2023) Arceri, Veronica ++; Kane, Michael P
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    Evaluation of a pharmacist's impact on the use of glucagon-like peptide-1 receptor agonists for weight management in a family medicine setting.
    (Family Practice, 10/6/2022) Crocetta, Nicholas ++; Guay, Kyle; Watson, Alexandra
    Background: Glucagon-like peptide-1 receptor (GLP-1) agonists carry benefits and risks that must be evaluated prior to use and monitored throughout weight management therapy. Pharmacists possess the accessibility and extensive medication knowledge to evaluate and monitor the use of GLP-1 therapy in weight management patients. Objective: Evaluate the clinical and financial impact of a pharmacist-directed weight management service utilizing GLP-1 receptor agonists in a family practice setting. Methods: A retrospective cohort study including patients at 2 family practices, aged 18 and older, prescribed a weight management GLP-1 between October 1, 2021 and March 1, 2022 was performed. Patients who met inclusion and were prescribed a weight loss GLP-1 but were not managed by the clinical pharmacist were compared with the pharmacist cohort. Descriptive statistics and inferential statistics including an independent t-test were used in the data analysis. Results: There were 46 and 39 patients identified in the clinical pharmacist and primary care physician cohorts respectively. Patients in the clinical pharmacist cohort achieved a mean body weight reduction of 9.32% compared to 5.11% body weight reduction for patients in the primary care physician cohort (P = 0.01). There were 63 months identified of inappropriate GLP-1 therapy deprescribed in the clinical pharmacist cohort resulting in an estimated cost savings of $101,985.66. Conclusions: The implementation of a pharmacist-led weight management clinic in 2 family medicine offices resulted in a significant reduction in body weight and reduction in total costs to the healthcare system compared to patients receiving weight management services from their primary care physician alone.
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    Implementation of an anabolic therapy program and follow-up of patients prescribed abaloparatide: real-world results of a pharmacist-led osteoporosis clinic
    (Current Trends in Endocrinology, 2022) Kane, Michael P; Arceri, Veronica R ++; Quinn, Hugh B ++; Telese, Mallory ++; Racz, Michael J; Busch, Robert S
    Utilizing anabolic osteoporosis therapies presents with challenges, including patient acceptance of injections, addressing medication safety concerns, and achieving medication access. We developed a pharmacist-run clinic to ensure the safe and effective use of these therapies. Primary endpoints were comparison of dual energy X-ray absorptiometry (DXA) T-scores and bone mineral density (BMD) values of the total hip, femoral neck, spine, and wrist at baseline, after abaloparatide therapy, and following 1 year of follow-on antiresorptive therapy. The secondary endpoint was the number of documented fractures during the evaluation period. 146 patients were referred for abaloparatide treatment. Ninety-one patients initiated treatment: average age was 66.7 (± 7.7) years, 56% had a history of osteoporotic fracture, baseline T-Scores of the femoral neck and spine were -2.5 (± 0.7), and -2.4 (± 1.3), respectfully. Mean length of therapy was 12 ± 2 months (range 9-18 months). T-scores and BMD significantly improved at all sites except for a significant decrease in T-score at the 1/3 radius. After 1 year of follow-on anti-resorptive treatment, T-scores and BMD significantly increased at the total hip and at the lumbar spine compared to post-abaloparatide, with nonsignificant changes in the femoral neck and 1/3 radius. There was one reported fracture. Eighteen patients (19.8%) discontinued therapy due to adverse drug reactions and there was a 72.5% medication persistence rate. Abaloparatide is effective in increasing BMD and T-scores and in preventing osteoporosis-related fractures. While significant barriers to anabolic osteoporosis treatment remain, involvement of a pharmacist-led clinic may increase medication persistence.
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    The Occurrence and Burden of Hypophosphatasia in an Ambulatory Care Endocrinology Practice.
    (Endocrine Practice, 7/21/2021) Quinn, Hugh B ++; Busch, Robert S; Kane, Michael P
    OBJECTIVE: Hypophosphatasia (HPP) is an inherited disease resulting from loss-of-function mutations in the ALPL gene encoding tissue-nonspecific alkaline phosphatase. The presentation and severity of the disease are highly variable, ranging from perinatal onset with high mortality rates to adult identification with low mortality rates and symptoms ranging from minimal to severe. Moderate forms of HPP typically manifest during middle age and are often undiagnosed. The objective of this study was to determine the occurrence and burden of HPP in an ambulatory care endocrinology practice. METHODS: Potential subjects were identified with a computerized text search of patient electronic medical records. Search terms included serum alkaline phosphatase (ALP) levels of