Health and lifestyle behaviors in colorectal cancer survivors with and without Lynch syndrome.
Loading...
Issue Date
1/11/2020
Authors
Donato, Kirsten M*
Moore, Katelyn*
Parker, Wendy M
Peterson, Susan K
Gritz, Ellen R
Amos, Christopher I
Lu, Karen H
Lynch, Patrick M
Rodriguez-Bigas, Miguel A
You, Y Nancy
Degree
Advisor
Committee Members
Journal Title
Journal ISSN
Volume Title
Abstract
Lynch syndrome (LS), a hereditary cancer syndrome, accounts for approximately 3% of colorectal cancers (CRC). Positive health behaviors and surveillance are preventive strategies, but research on whether recommended behavioral guidelines are followed by individuals with LS is limited. Additional health education and promotion could be beneficial to the improved survivorship of CRC survivors. Explore health and lifestyle behaviors in CRC survivors with and without LS. We conducted a case-control study of CRC survivors with and without LS using a mailed questionnaire. Recruitment was conducted via patient registries at The University of Texas MD Anderson Cancer Center (cases n = 33; controls n = 75) and through social media (cases n = 42). CRC survivors with and without LS in our study had substantially lower smoking prevalence (5.5% and 2.7%) compared to national prevalence (18.0%). However, they had higher levels of alcohol consumption (36.8% and 10.3% for male and female LS survivors, respectively, and 35.8% and 22.0% for male and female sporadic survivors, respectively) compared to national prevalence of 13.88% for males and 6.02% for females. Both groups of CRC survivors participate in negative health behaviors that impact survivorship. More research is needed to examine the relationship between personal engagement in preventive behaviors and patient-provider relationships to improve health behaviors and explore strategies for intervention. Additionally, better health education and lifestyle change recommendations would promote and reinforce positive health outcomes in the CRC population and especially in LS survivors.
Citation
Donato KM, Moore K, Parker WM, Peterson SK, Gritz ER, Amos CI, Lu KH, Lynch PM, Rodriguez-Bigas MA, You YN, Burton-Chase AM. Health and lifestyle behaviors in colorectal cancer survivors with and without Lynch syndrome. J Community Genet. 2020 Jan;11(1):59-63. doi: 10.1007/s12687-019-00421-y. Epub 2019 Apr 23. PMID: 31016603; PMCID: PMC6962402.