The role of lipids and lipid metabolites in urinary bladder dysfunction induced by partial outlet obstruction.

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dc.contributor.authorHass, Martha A
dc.contributor.authorLevin, Robert M
dc.contributor.orcidhttps://orcid.org/0000-0002-3981-9860
dc.date.accessioned2023-10-25T13:53:40Z
dc.date.available2023-10-25T13:53:40Z
dc.date.issued2003-01
dc.descriptionClick on the Resource Link to access the article (may not be free).
dc.description.abstractBenign prostate hyperplasia (BPH) frequently progresses to cause partial outlet obstruction of the urinary bladder, resulting in a range of symptoms including urine retention, poor flow, nocturia, and detrusor instability. Over 80% of males 50 to 60 years of age and older have various degrees of bladder outlet obstruction secondary to BPH that results in urinary dysfunction. The urinary dysfunction in men with BPH is related to functional, structural, and biochemical changes that occur in both the smooth muscle and urothelial components of the urinary bladder during urethral obstruction by the enlarged prostate. However, the specific pathophysiology that leads to BPH symptoms remains unknown. The ability to develop rational therapeutic interventions for the treatment of bladder dysfunction associated with BPH requires an understanding of the pathological changes that occur in the underlying cellular mechanisms responsible for maintaining normal bladder function.
dc.description.urihttps://doi.org/10.1007/978-1-4419-8889-8_16
dc.identifier.citationHass MA, Levin RM. The role of lipids and lipid metabolites in urinary bladder dysfunction induced by partial outlet obstruction. Adv Exp Med Biol. 2003;539(Pt A):217-37. doi: 10.1007/978-1-4419-8889-8_16. PMID: 15088907.
dc.identifier.issn0065-2598
dc.identifier.other15088907
dc.identifier.urihttps://hdl.handle.net/20.500.14303/212
dc.language.isoen
dc.publisherKluwer Academic/Plenum Publishers
dc.relation.ispartofAdvances in Experimental Medicine and Biology
dc.rightsThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). http://rightsstatements.org/vocab/InC/1.0/
dc.subjectLipid Metabolism
dc.subjectUrinary Bladder / metabolism
dc.subjectUrinary Bladder Neck Obstruction / metabolism
dc.subjectUrination Disorders / metabolism
dc.subjectAnimals
dc.titleThe role of lipids and lipid metabolites in urinary bladder dysfunction induced by partial outlet obstruction.
dc.typeArticle
local.departmentprogramDepartment of Life Sciences
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