Off-label use of liraglutide in the management of a pediatric patient with type 2 diabetes mellitus.
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Issue Date
2013
Authors
Micale, Sara J ++
Kane, Michael P
Hogan, Eileen
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Abstract
Liraglutide is a glucagon-like peptide 1 (GLP-1) analog indicated for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise in adults. Liraglutide lowers blood glucose levels by stimulating insulin secretion and decreasing glucagon release in glucose-dependent manners, increases satiety, and delays gastric emptying. Liraglutide, unlike metformin and insulin, is not approved for use in the pediatric population. We report the successful off-label use of liraglutide in an obese, 16 year old Caucasian female with type 2 diabetes mellitus.
Citation
Micale SJ, Kane MP, Hogan E. Off-label use of liraglutide in the management of a pediatric patient with type 2 diabetes mellitus. Case Rep Pediatr. 2013;2013:703925. doi: 10.1155/2013/703925. Epub 2013 Oct 3. PMID: 24222881; PMCID: PMC3814067.
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