Post Hoc Assessment of Time to Clinical Response Among Adults Hospitalized with Community-Acquired Bacterial Pneumonia Who Received Either Lefamulin or Moxifloxacin in 2 Phase III Randomized, Double-Blind, Double-Dummy Clinical Trials.

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dc.contributor.authorLodise, Thomas P
dc.contributor.authorColman, Sam
dc.contributor.authorStein, Daniel S
dc.contributor.authorFitts, David
dc.contributor.authorGoldberg, Lisa
dc.contributor.authorAlexander, Elizabeth
dc.contributor.authorScoble, Patrick J
dc.contributor.authorSchranz, Jennifer
dc.contributor.orcidhttps://orcid.org/0000-0002-4730-0655
dc.date.accessioned2025-02-11T19:49:22Z
dc.date.available2025-02-11T19:49:22Z
dc.date.issued2020-05
dc.description.abstractTime to clinical response, a proxy for hospital "discharge readiness," was compared between CABP inpatients who received lefamulin or moxifloxacin in the Lefamulin Evaluation Against Pneumonia (LEAP) trials. The analysis included 926 inpatients. A short and comparable median time to clinical response (4 days) was observed in both treatment groups.
dc.description.urihttps://doi.org/10.1093/ofid/ofaa145
dc.description.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/pmc7240345
dc.identifier.citationLodise T, Colman S, Stein DS, Fitts D, Goldberg L, Alexander E, Scoble PJ, Schranz J. Post Hoc Assessment of Time to Clinical Response Among Adults Hospitalized with Community-Acquired Bacterial Pneumonia Who Received Either Lefamulin or Moxifloxacin in 2 Phase III Randomized, Double-Blind, Double-Dummy Clinical Trials. Open Forum Infect Dis. 2020 Apr 24;7(5):ofaa145. doi: 10.1093/ofid/ofaa145. PMID: 32462049; PMCID: PMC7240345.
dc.identifier.issn2328-8957
dc.identifier.other32462049
dc.identifier.urihttps://hdl.handle.net/20.500.14303/861
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofOpen Forum Infectious Diseases
dc.rightsThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). http://rightsstatements.org/vocab/InC/1.0/
dc.subjectcommunity-acquired bacterial pneumonia
dc.subjectfluoroquinolones
dc.subjectlefamulin
dc.subjectpatient discharge
dc.subjecttime to clinical response
dc.titlePost Hoc Assessment of Time to Clinical Response Among Adults Hospitalized with Community-Acquired Bacterial Pneumonia Who Received Either Lefamulin or Moxifloxacin in 2 Phase III Randomized, Double-Blind, Double-Dummy Clinical Trials.
dc.typeArticle
local.departmentprogramDepartment of Pharmacy Practice
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